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Part II of this study addresses the design
2018-11-12

Part II of this Aminoallyl-dUTP - Cy3 Supplier study addresses the design in a supposed operationalization phase that was guided by both data sets of Part I. Furthermore, the data were used to develop a checklist for architects. The design was based on the joint description of a fictional persona by
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synthase In summary many preclinical and
2018-11-12

In summary, many preclinical and clinical studies demonstrate that stem cell regeneration of the myocardium is an alternative efficacious treatment for both acute and chronic myocardial injury. Although therapeutic timing and specific safety concerns such as ventricular arrhythmia are always debate
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br Discussion The incidence of
2018-11-12

Discussion The incidence of appendiceal diverticulosis is 0.004–2.1% in appendectomy specimens and 0.2–0.66% in autopsy cases. Appendiceal diverticula are traditionally categorized as true diverticula or pseudodiverticula. True diverticula are congenital and are composed of the following four lay
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Cost effective analysis also showed favorable results With r
2018-11-12

Cost-effective analysis also showed favorable results. With regard to long-term outcomes, no published studies have demonstrated significant differences in freedom from reoperation, differences in degree of postoperative mitral regurgitation, or differences in long-term survival between sternotomy a
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Koenig et al reported a case
2018-11-12

Koenig et al reported a case of recurrent hemorrhagic strokes associated with paraneoplastic disseminated intravascular coagulation due to occult large cell carcinoma. In our patient, although we did not find any evidence of disseminated intravascular coagulation, we could not ignore this potential
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In silico screening systems a combination of focused
2018-11-12

In silico screening systems, a combination of focused in vitro cell-based models and computer based algorithms employ a variety of different high-throughput and high-content screening technologies. Cell-specific biomarkers on gene, protein or metabolite levels can be measured by toxicogenomics, toxi
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In order to analyze and identify
2018-11-12

In order to analyze and identify the obtained mineral, additional Raman spectroscopy was performed (Putnis, 1992). It is known that calcium phosphate minerals show a characteristic peak at 960cm (Koutsopoulos, 2002; Sauer et al., 1994). All of the samples analyzed in the present study showed a stron
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In our model DNA damage forces
2018-11-12

In our model, DNA damage forces cells into cellular senescence, whereas ATM-dependent and p53-antagonized cytokine secretion activates BMP2/JAK-STAT signaling and stimulates the differentiation process in a progressive feed-forward manner. This senescent state is very different from the GFAP-associa
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br Results We next sought
2018-11-12

Results We next sought to look at the correlation between the methylation and expression levels of each somatic cell and the iPSCs that were generated from it. We looked at the methylation status for CpG island or nonisland CpG promoters in the four expression groups that we generated previously
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Why ectopic BRIGHT knockdown was capable of stimulating
2018-11-12

Why ectopic BRIGHT knockdown was capable of stimulating reprogramming by the conventional 4F method but not singularly is unclear. While BRIGHT levels in MEFs are modest compared to hematopoietic tissues (Webb et al., 2011), we were only able to achieve ∼75% reduction in transcript levels (Figure S1
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br Conclusions br Author contributions
2018-11-12

Conclusions Author contributions Conflicts of interest Acknowledgments Introduction Self-renewal is an integrated proliferation control that maintains undifferentiated states of stem cells. The integrated control is achieved by multilayered regulatory networks involving complex interp
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br Materials and methods br Results br Discussion
2018-11-12

Materials and methods Results Discussion The roles of endogenous stem/progenitor D-Luciferin in adult pancreatic tissue homeostasis, acute/chronic injury response and tumor initiation remain uncertain. However, it is now clear that a subset of pancreatic duct cells are capable of initiatin
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br Macrophage roles in cardiac injury responses While cTMs m
2018-11-12

Macrophage roles in cardiac injury responses While cTMs may play an important role in cardiac homeostasis, they are likely to be amongst the first cell types to react to cardiac tissue damage. Following injury, a robust inflammatory response involves secretion of various cytokines and infiltratio
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br Results The Hot Start experience and outcomes
2018-11-12

Results The Hot Start experience and outcomes were embodied in established and conceived infrastructure provided by its membership. This was both as originally proposed and subsequently informed and amended in the course of operational experience as follows. Discussion The EBiSC Hot Start yie
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br Materials and methods br Author
2018-11-12

Materials and methods Author disclosure statement 5. Acknowledgments This work was supported by the UK Medical Research Council grants G0701172 and G0801061. We thank Dr. Yacoub Khalaf, director of the Assisted Conception Unit of Guy\'s and St. Thomas\' NHS Foundation Trust and his staff fo
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