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br Experimental design materials and methods br Acknowledgem
2018-11-07
Experimental design, materials and methods Acknowledgements This research was funded by Région Centre (project ADRIEN) and INRA meta-program SMaCH – Sustainable Management of Crop Health (project SESAME). We are grateful to the town councils of Fleury-les-Aubrais, Saint-Jean-de-Braye, Saran an
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br Methods br Results br Discussion In a transdiagnostic sam
2018-11-07
Methods Results Discussion In a transdiagnostic sample of anxious youth, greater laboratory-assessed vigilance to threat was associated with greater real-world use of avoidance (distraction and suppression) in the wake of negative events. Given the high clinical relevance of real-world avoi
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At the cellular level DCDC is involved in
2018-11-07
At the cellular level DCDC2 is involved in processes such as cellular defense response, dendrite morphogenesis, intracellular signal transduction, regulation of smoothened signaling pathway, regulation of Wnt signaling pathway, and regulation of cilium assembly. At the systems level, DCDC2 is correl
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The auditory social versus non social contrast
2018-11-07
The auditory social versus non-social contrast, which was used at all five age points from 0 to 24 months of age, revealed evidence of a developmental change in specialisation for auditory social stimuli across infancy. Whilst the 0–2 (Cohort 1) and 4–8 (Cohort 2) month olds evidenced significant Hb
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Corbusier for a good part of his career
2018-11-06
Corbusier, for a good part of his career, seemingly showed neither hesitation nor fear of the capacious world out there, which nonetheless was merely his public persona. Immediately after he completed the Villa Savoye, Corbusier undertook the venture, as both the developer and the architect, to buil
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Concerning clinical implications of CSC
2018-11-06
Concerning clinical implications of CSC, HCC expresses some de-differentiation markers in the fetal liver, such as AFP, CD133 or OV-6 (expression) in poorer prognoses. In fact, a small population of CD133+ isosafrole could be present in hepatoblastoma as well as in HCC, suggesting the possibility of
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(S)-Crizotinib Introduction Mesenchymal stem cells MSCs
2018-11-06
Introduction Mesenchymal stem (S)-Crizotinib (MSCs) are the best studied subpopulations of stem/progenitor cells in bone marrow capable of differentiating into various nonhematopoietic cells, and they are isolated by their adherence to tissue culture surfaces. They are readily isolated from patient
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br Results The ligation and nonligation groups were
2018-11-06
Results The ligation and nonligation groups were well matched for sizes of internal ring orifices (p = 0.707; Table 1) and incidence of coexisting Pantaloon hernia (p = 0.826). The range of operation times was 65–146 minutes in the ligation group and 72–164 minutes in the nonligation group. The a
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The use of MaSCs from GFP mice for
2018-11-06
The use of MaSCs from GFP mice for in vivo transplant into wild type recipients enabled us to examine the purity of FACS-gated basal and luminal cell populations from the regenerated GFP glands. All epithelial cytochalasin d (GFP positive) were converged in the CD24+ population, while the combinati
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br Experimental br Results and discussions The modulation
2018-11-06
Experimental Results and discussions The modulation of the dynamic sensing range of electrochemical aptasensor is of great significance but facing great challenges. The design and principle of the extraordinary tunable dynamic range of the electrochemical aptasensor is shown in Scheme 1, the k
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br Materials and methods br
2018-11-06
Materials and methods Results Discussion To the best of our knowledge, the present study constitutes the first report describing diet-mediated inhibition of the expansion of the MaSC-enriched (CD29hiCD24+Lin−) epithelial subpopulation in vivo that may relate to decreased susceptibility to m
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In this study we first demonstrated that the CD population
2018-11-06
In this study, we first demonstrated that the CD44+ population isolated from the HCT-15 human colon cancer cell line not only exhibited multiple in vitro features of CSCs but also showed higher in vivo tumorigenicity. In accordance, knocking down CD44 expression in HCT-15 Phos-tag Biotin BTL-105 res
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Ras MAPK signaling is often deregulated
2018-11-06
Ras–MAPK signaling is often deregulated and is constitutively active in many types of cancers including pancreatic, colon, lung, melanoma and breast (Dunn et al., 2005). Activation of PI3K, Rac-1 and JNK was necessary for bFGF-induced fibroblast migration and blocking the activation of PI3K, Rac-1 o
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In our study ERK and JNK inhibitors
2018-11-06
In our study, ERK and JNK inhibitors effectively inhibited the migration of glioma buy hydroxychloroquine sulfate while the effect of the p38 inhibitor was not as significant. Hence, we further evaluated the effect of downregulation of uPAR and cathepsin B on the expression of ERK and JNK. Reductio
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br Introduction Despite the remarkable progress made during
2018-11-06
Introduction Despite the remarkable progress made during the past half century in the treatment of cardiovascular disease, which is increasingly effective in dealing with the acute stages of life-threatening pathology, they often extend the life of the patient at the expense of generating a chron
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